Program

Friday, 10 July 2015 – Wicklow Meeting Room 2

07:30 - 09:00
09:00 - 09:15
09:15 - 10:15
10:15 - 10:45
10:45 - 11:10
11:10 - 11:50
11:50 – 12:30

12:30 - 13:30
13:30 - 14:10
14:10 - 14:50

14:50 - 15:30

15:30 - 16:00
16:00 - 16:40
16:40 - 17:05
17:05 - 17:30
17:30 - 18:00
19:30

Registration
Welcome
Keynote: Des Higgins. Making and using extremely large multiple sequence alignments.
Morning break
David Kreil. Setting the context
Hubert Rehrauer. Prognostic value of cross-omics screening for cancer survival.
Marta R. Hidalgo. Functional hallmarks in clear cell renal cell carcinoma grade and stage progression revealed by changes in signalling circuit activities.
Lunch break
Jari Björne. Cancer Progression Classification for Mutation Analysis.
Susmita Datta. Exploring the Importance of Cancer Pathways by Meta-Analysis of Differential Protein Expression Networks in Three Different Cancers.
Pramila Tata. Multi-Omics analysis for understanding the molecular basis of Lung Adenocarcinoma.
Afternoon break
Alejandra Cervera. A pipeline for exploratory and pathway analysis of NGS data.
Lan Hu. Biolfuid exosomes: a new player for genomic profiling.
Djork-Arné Clevert. Rectified Factor Networks for Deep Learning.
Olivier Gevaert. Multi-omics fusion for cancer data.
Conference dinner

Saturday, 11 July 2015 – room t.b.a.

09:05 - 09:15
09:15 - 10:15

10:15 - 10:45
10:45 - 11:10
11:10 - 11:50

11:50 – 12:30

12:30 - 13:30
13:30 - 13:50

13:50 - 14:30

14:30 - 14:50
14:50 - 15:30

15:30 - 16:00
16:00 - 16:20

16:20 - 17:00

17:00 - 17:30

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Get the abstracts!

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Keynotes

Des Higgins, PhD
Presentation Title: Making and using extremely large multiple sequence alignments.

Short Bio: Des Higgins is professor of Bioinformatics in University College Dublin, Ireland and has been working on sequence alignment and molecular evolution since the mid 1980s. He originated the widely used Clustal package and continues to develop and maintain multiple sequence alignment algorithms and software. He also works on the analysis of high throughput genomics data, especially in the application of multivariate analysis methods for data integration. He has published more than 130 peer-reviewed articles in bioinformatics, sequence alignment and genomics with an h-index of 54.

Christopher E. Mason, PhD
Presentation Title: Leveraging short and long reads for optimal RNA-Sequencing with CAMDA data set #1.

Abstract: To sequence more or not to sequence more? That is the question. Is it better to suffer the slings and arrows of outrageous haplotypes or not? Here we use the SEQC datasets to titrate reads lengths at varying scales to discern the impact of read length on quantification, splicing detection, and detection efficiency, and we show that for expression-based goals, reads generally do not need to go beyond 50bp. However, for splicing detection, longer reads significantly improve one's ability to classify and detect isoform changes. Finally, we comment on the significance of low-abundance isoforms that can reveal new roles of subsets of RNA. These results can help plan experimental design for both large and small-scale RNA-seq studies.

Short Bio: Christopher E. Mason completed his dual B.S. in Genetics and Biochemistry from University of Wisconsin-Madison in 2001, his Ph.D. in Genetics from Yale University in 2006, and his post-doctoral training at Yale Medical School, while also holding a fellowship at Yale Law School. In 2009, Dr. Mason founded his laboratory as an assistant professor at Weill Cornell Medical College in the Department of Physiology and Biophysics and at the Institute for Computational Biomedicine. Professor Mason also holds an appointment in the Tri-Institutional Program on Computational Biology and Medicine between Cornell, Memorial Sloan-Kettering Cancer Center and Rockefeller University and he also has an appointment at the Weill Cornell Cancer Center and the Brain and Mind Research Institute. In 2013, he won the Hirschl-Weill-Caulier Career Scientist Award. In 2014, he won the Vallee Foundation Young Investigator Award, the CDC Honor Award for Standardization of Clinical Testing, and he was just named as one of the “Brilliant Ten” Scientists in the world by Popular Science magazine. In 2015, he became the first WorldQuant Foundation Research Scholar, was recently promoted to associate professor, and his work has been featured across the world in over 300 media outlets.

The scientific program includes keynotes by leading researchers in the field and selected presentations of contest dataset analyses. The two-day meeting will also feature a social dinner with and opportunities for informal discussions. The conference will close on Saturday in time for delegates to join to the evening reception of ISMB/ECCB.
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PAST KEYNOTE SPEAKERS

Atul Butte, MD, PhD
Atul Butte, MD, PhD
Stanford University School of Medicine

Nikolaus Rajewsky, PhD
Nikolaus Rajewsky, PhD
Max-Delbrück-Center for Molecular Medicine

Terry Speed, PhD
Terry Speed, PhD
The Walter and Eliza Hall Institute of Medical Research

Sandrine Dupoit, PhD
Sandrine Dudoit, PhD
University of California, Berkeley

John Quackenbush, PhD
John Quackenbush, PhD
Harvard School of Public Health

Eran Segal, PhD
Eran Segal, PhD
Weizmann Institute of Science

John Storey, PhD
John Storey, PhD
Princeton University

Chris Sander, PhD
Chris Sander, PhD
Memorial Sloan Kettering Cancer Center

Temple F. Smith, PhD
Temple F. Smith, PhD
Boston University

IMPORTANT DATES
Extended Abstract Proposals Due20 May 2015
Abstract Deadline for Poster Submission 25 May 2015
Notification of Accepted Contributions30 May 2015
Early Registration Closes7 Jun 2015
CAMDA2015 Conference10–11 Jul 2015
ISMB 2015 Conference11–14 Jul 2015
Full Paper Submission Click to save the dates!25 Sep 2015
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Exosome Diagnostics

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